The DHT pathway, and where each drug blocks it
Testosterone becomes DHT at a single enzyme step with three isoenzymes; DHT then binds the androgen receptor in a genetically susceptible follicle, and the follicle miniaturises. Finasteride closes Type II, dutasteride closes all three, which is why lowering DHT slows the loss and why the two drugs lower it by different amounts.
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Every number printed on this figure, and where it came from
Each quantity the diagram prints, the sentence it was taken from, and the guide that sentence is in. The build refuses to publish if one of these sentences is no longer in the guide it names.
| Value | What it is, and the sentence behind it | Source guide |
|---|---|---|
| 1 mg daily | Finasteride dose printed under the drug name “The FDA-approved dose for male pattern hair loss is 1 mg taken orally once daily” | Complete Guide to Finasteride for Hair Loss |
| 0.5 mg daily | Dutasteride dose printed under the drug name “dutasteride is used at a dose of 0.5 mg daily” | Dutasteride vs Finasteride: Which Is Better for Hair Loss? |
| 10 x testosterone | DHT potency, printed under the DHT node “DHT is approximately 10 times more potent than testosterone” | DHT and Hair Loss: Complete Explanation |
| 2-5 x | DHT receptor affinity relative to testosterone — the reason the receptor step matters “has 2-5 times higher affinity for androgen receptors” | DHT and Hair Loss: Complete Explanation |
| 46% | Share of genetic risk attributed to the AR gene, printed under the receptor node “Accounts for roughly 46% of the genetic risk for pattern hair loss” | DHT and Hair Loss: Complete Explanation |
| 70-71% | Serum DHT reduction on finasteride — the upper bar “Serum DHT reduction: 70-71%” | Dutasteride vs Finasteride: Which Is Better for Hair Loss? |
| 90-98% | Serum DHT reduction on dutasteride — the lower bar “Serum DHT reduction: 90-98%” | Dutasteride vs Finasteride: Which Is Better for Hair Loss? |
| 68% | The finasteride guide's own serum DHT figure, which is not T02's “serum DHT levels by 68%” | Complete Guide to Finasteride for Hair Loss |
| 92-94.7% | The DHT guide's own serum DHT figure for dutasteride “Serum: 92-94.7% reduction” | DHT and Hair Loss: Complete Explanation |
| 80-90% | Share of men in whom FINASTERIDE slows further loss — the payoff line “finasteride slows down further hair loss in approximately 80-90% of men who take it” | Complete Guide to Finasteride for Hair Loss |
| 14 days | How long the block lasts after finasteride is stopped “DHT returns to normal within 14 days of stopping finasteride” | DHT and Hair Loss: Complete Explanation |
| 4-6 months | How long the block lasts after dutasteride is stopped “DHT remains suppressed for 4-6 months” | Dutasteride vs Finasteride: Which Is Better for Hair Loss? |
Where this figure appears
DHT and Hair Loss: Complete Explanation · Complete Guide to Finasteride for Hair Loss · Dutasteride vs Finasteride: Which Is Better for Hair Loss?