Efficacy and Safety of TargetCool + Benev Exosomes in Patients With Hair Thinning

The registered record

Accession number

NCT06999408

Lead sponsor

Recens Medical, Inc. (industry)

Collaborators

Benev Company, Inc.

Registered conditions naming hair loss

AlopeciaHair Thinning

Also registered on this record

Hair Diseases

Official title

A Prospective, 8-Month, Randomized Pilot Study of TargetCool™ Cryo-Modulation and BENEV Exosome Regenerative Complex+® for Hair Density Enhancement in Adults With Non-Scarring Hair Thinning

The first row holds the registered conditions that placed this trial on the pipeline; the second holds everything else the sponsor registered on the same record. Both are shown, and shown apart rather than shaded differently, because leaving the second out would make this trial look more like a hair-loss study than its registration says it is — and because a distinction carried only by colour is not a distinction for every reader.

Interventions

• DeviceScalp tattoo
• DeviceCanfield HairMetrix®
• DeviceTargetCool
• DeviceMicroneedle-facilitated lidocaine application

Names and types as registered. The sponsors' free-text descriptions of these interventions are not reproduced: they are written by the party with an interest in the result, and reprinting them inside this site's layout would lend them this site's voice.

Design

Study type

interventional

Phase

Not applicable

Allocation

randomized

Masking

none

Primary purpose

treatment

Enrolment

15 participants (estimated)

Sites

1 location in United States

What it measures

1. Change in Terminal Hair Counts

   Time frame: 32 weeks (8 months)

2. Change in Vellus Hair Counts

   Time frame: 32 weeks (8 months)

3. Change in Total Hair Counts

   Time frame: 32 weeks (8 months)

4. Change in average hair width

   Time frame: 32 weeks (8 months)

Primary outcome measures only, as registered. What a trial chose to measure, and when, is the most informative thing about it that is knowable before it reports — a hair-count endpoint at 24 weeks and a patient-satisfaction endpoint at 12 weeks are not the same study.

Who can take part

Sex

all

Age

18 Years to 70 Years

Healthy volunteers

not accepted

A summary of three registered fields, not the eligibility criteria. The full inclusion and exclusion criteria, the recruiting sites and the study contacts are on the registry record, which is the only place they are maintained. This site has no relationship with this trial and cannot refer anyone to it.

Registered dates

Study start

16 September 2025 (actual)

Primary completion

May 2026 (estimated)

Study completion

May 2026 (estimated)

First posted

31 May 2025 (actual)

Last update posted

9 March 2026 (actual)

"Estimated" and "actual" are the registry's own labels: an estimated date is a plan, and plans move. A date is printed at the precision it was registered at: a primary completion registered as 2026-05 is a month, and rendering it as 1 May 2026 would invent a day the sponsor did not register.

Results

This trial has not reported results. ClinicalTrials.gov holds no results record for it. That is the ordinary state of a trial that is running or about to run, and it means there is nothing here to tell you about whether the intervention works — including nothing negative. If this page implied otherwise it would be wrong.

On this site

Guides covering the condition this trial is registered for. They are about published evidence; this page is about a registration, and the two do not overlap.

Diffuse Thinning vs. Pattern Baldness: How to Tell the Difference (2026 Guide)How to Tell If You're Going Bald: Early Signs & Self-Assessment Guide (2026)

Where this came from

Read from the ClinicalTrials.gov API on 6 September 2026 and rebuilt into this page without alteration. ClinicalTrials.gov is a service of the U.S. National Library of Medicine and is the authority on this record; where this page and the registry disagree, the registry is right. This page is not affiliated with or endorsed by NLM or NIH, or with the sponsor of this trial.

Open NCT06999408 on ClinicalTrials.gov · All 157 trials in the pipeline